Heatmap
6 Clusters
| 1 |
440 |
| 2 |
273 |
| 3 |
785 |
| 4 |
630 |
| 5 |
285 |
| 6 |
387 |
| Total |
2800 |
Expression Boxplots of Representative Genes
Expression Boxplots of Hrs, Gprk2, InR, Akt1 (Akt), and Pi3K92E
Enrichments
Cluster 1
## Uploading data to Enrichr... Done.
## Querying GO_Biological_Process_2018... Done.
## Querying GO_Molecular_Function_2018... Done.
## Querying KEGG_2019... Done.
## Parsing results... Done.
GO Biological Processes
KEGG 2019
Cluster 2
## Uploading data to Enrichr... Done.
## Querying GO_Biological_Process_2018... Done.
## Querying GO_Molecular_Function_2018... Done.
## Querying KEGG_2019... Done.
## Parsing results... Done.
GO Biological Processes
KEGG 2019
Cluster 3
## Uploading data to Enrichr... Done.
## Querying GO_Biological_Process_2018... Done.
## Querying GO_Molecular_Function_2018... Done.
## Querying KEGG_2019... Done.
## Parsing results... Done.
GO Biological Processes
KEGG 2019
Cluster 4
## Uploading data to Enrichr... Done.
## Querying GO_Biological_Process_2018... Done.
## Querying GO_Molecular_Function_2018... Done.
## Querying KEGG_2019... Done.
## Parsing results... Done.
GO Biological Processes
KEGG 2019
Cluster 5
## Uploading data to Enrichr... Done.
## Querying GO_Biological_Process_2018... Done.
## Querying GO_Molecular_Function_2018... Done.
## Querying KEGG_2019... Done.
## Parsing results... Done.
GO Biological Processes
KEGG 2019
Cluster 6
## Uploading data to Enrichr... Done.
## Querying GO_Biological_Process_2018... Done.
## Querying GO_Molecular_Function_2018... Done.
## Querying KEGG_2019... Done.
## Parsing results... Done.
GO Biological Processes
KEGG 2019
Enrichment Summary
KEGG
Gene Expression Plots
Cluster 1
Cluster 2
Session Info
## R version 4.0.5 (2021-03-31)
## Platform: x86_64-apple-darwin17.0 (64-bit)
## Running under: macOS Big Sur 10.16
##
## Matrix products: default
## BLAS: /Library/Frameworks/R.framework/Versions/4.0/Resources/lib/libRblas.dylib
## LAPACK: /Library/Frameworks/R.framework/Versions/4.0/Resources/lib/libRlapack.dylib
##
## locale:
## [1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8
##
## attached base packages:
## [1] grid parallel stats4 stats graphics grDevices utils
## [8] datasets methods base
##
## other attached packages:
## [1] cowplot_1.1.1 seqLogo_1.56.0
## [3] MotifDb_1.32.0 enrichR_3.0
## [5] ggpubr_0.4.0 data.table_1.14.0
## [7] DT_0.17 msigdbr_7.2.1
## [9] forcats_0.5.1 dplyr_1.0.5
## [11] purrr_0.3.4 readr_1.4.0
## [13] tidyr_1.1.3 tibble_3.1.0
## [15] tidyverse_1.3.0 factoextra_1.0.7
## [17] cluster_2.1.1 stringr_1.4.0
## [19] enrichplot_1.13.0 ReactomePA_1.34.0
## [21] clusterProfiler_3.18.1 BSgenome.Dmelanogaster.UCSC.dm6_1.4.1
## [23] BSgenome_1.58.0 rtracklayer_1.50.0
## [25] pheatmap_1.0.12 geneplotter_1.68.0
## [27] annotate_1.68.0 XML_3.99-0.6
## [29] reshape_0.8.8 lattice_0.20-41
## [31] gridExtra_2.3 RColorBrewer_1.1-2
## [33] kableExtra_1.3.4 Biostrings_2.58.0
## [35] XVector_0.30.0 scales_1.1.1
## [37] reshape2_1.4.4 knitr_1.31
## [39] biomaRt_2.46.3 GenomicFeatures_1.42.3
## [41] AnnotationDbi_1.52.0 genefilter_1.72.1
## [43] ggplot2_3.3.3 DESeq2_1.30.1
## [45] SummarizedExperiment_1.20.0 Biobase_2.50.0
## [47] MatrixGenerics_1.2.1 matrixStats_0.58.0
## [49] GenomicRanges_1.42.0 GenomeInfoDb_1.26.7
## [51] IRanges_2.24.1 S4Vectors_0.28.1
## [53] BiocGenerics_0.36.0
##
## loaded via a namespace (and not attached):
## [1] utf8_1.2.1 tidyselect_1.1.0 htmlwidgets_1.5.3
## [4] RSQLite_2.2.6 BiocParallel_1.24.1 scatterpie_0.1.5
## [7] munsell_0.5.0 withr_2.4.1 colorspace_2.0-0
## [10] GOSemSim_2.16.1 highr_0.8 rstudioapi_0.13
## [13] ggsignif_0.6.1 DOSE_3.16.0 labeling_0.4.2
## [16] GenomeInfoDbData_1.2.4 polyclip_1.10-0 bit64_4.0.5
## [19] farver_2.1.0 rprojroot_2.0.2 downloader_0.4
## [22] vctrs_0.3.7 treeio_1.14.4 generics_0.1.0
## [25] xfun_0.22 BiocFileCache_1.14.0 R6_2.5.0
## [28] splitstackshape_1.4.8 graphlayouts_0.7.1 locfit_1.5-9.4
## [31] bitops_1.0-6 cachem_1.0.4 fgsea_1.16.0
## [34] DelayedArray_0.16.3 assertthat_0.2.1 ggraph_2.0.5
## [37] gtable_0.3.0 tidygraph_1.2.0 rlang_0.4.10
## [40] systemfonts_1.0.1 splines_4.0.5 rstatix_0.7.0
## [43] lazyeval_0.2.2 broom_0.7.6 checkmate_2.0.0
## [46] abind_1.4-5 BiocManager_1.30.12 yaml_2.2.1
## [49] modelr_0.1.8 crosstalk_1.1.1 backports_1.2.1
## [52] qvalue_2.22.0 tools_4.0.5 ellipsis_0.3.1
## [55] jquerylib_0.1.3 Rcpp_1.0.6 plyr_1.8.6
## [58] progress_1.2.2 zlibbioc_1.36.0 RCurl_1.98-1.3
## [61] prettyunits_1.1.1 openssl_1.4.3 viridis_0.5.1
## [64] haven_2.3.1 ggrepel_0.9.1 fs_1.5.0
## [67] magrittr_2.0.1 openxlsx_4.2.3 DO.db_2.9
## [70] reprex_2.0.0 reactome.db_1.74.0 hms_1.0.0
## [73] patchwork_1.1.1 evaluate_0.14 xtable_1.8-4
## [76] rio_0.5.26 readxl_1.3.1 compiler_4.0.5
## [79] crayon_1.4.1 shadowtext_0.0.7 htmltools_0.5.1.1
## [82] aplot_0.0.6 lubridate_1.7.10 DBI_1.1.1
## [85] tweenr_1.0.2 dbplyr_2.1.1 MASS_7.3-53.1
## [88] rappdirs_0.3.3 car_3.0-10 Matrix_1.3-2
## [91] cli_2.4.0 igraph_1.2.6 pkgconfig_2.0.3
## [94] rvcheck_0.1.8 GenomicAlignments_1.26.0 foreign_0.8-81
## [97] xml2_1.3.2 ggtree_2.4.2 svglite_2.0.0
## [100] bslib_0.2.4 webshot_0.5.2 rvest_1.0.0
## [103] digest_0.6.27 graph_1.68.0 rmarkdown_2.7
## [106] cellranger_1.1.0 fastmatch_1.1-0 tidytree_0.3.4
## [109] curl_4.3 Rsamtools_2.6.0 graphite_1.36.0
## [112] rjson_0.2.20 lifecycle_1.0.0 nlme_3.1-152
## [115] jsonlite_1.7.2 carData_3.0-4 viridisLite_0.4.0
## [118] askpass_1.1 fansi_0.4.2 pillar_1.6.0
## [121] fastmap_1.1.0 httr_1.4.2 survival_3.2-10
## [124] GO.db_3.12.1 glue_1.4.2 zip_2.1.1
## [127] bit_4.0.4 ggforce_0.3.3 stringi_1.5.3
## [130] sass_0.3.1 blob_1.2.1 memoise_2.0.0
## [133] ape_5.5
